Masters of Longevity - The Pulse

MoL Editorial20 Sept 2026
What Changes in the Human Hippocampus with Age? (MoL Editorial)

What Changes in the Human Hippocampus with Age?

A study of 40 postmortem brains maps a midlife shift in immune cells and a wider loss of cellular and genome organisation—but it does not show how to prevent cognitive decline.

Youtube - Dr. Stan Bradfield19 Sept 2026
Soon We'll Forget What Heart Attacks Are (Youtube - Dr. Stan Bradfield)

Soon We'll Forget What Heart Attacks Are

This piece previews a narrative-driven health feature about the evolving fight against heart attacks, tracing decades of research and prevention progress.

Key takeaways
  • Declines in smoking since the 1964 Surgeon General report contributed substantially to falling heart attack rates.
  • Blood pressure research from mid-20th century public studies established hypertension as a modifiable cardiovascular risk factor.
  • Recent advances in GLP-1 weight-loss drugs and PCSK9-targeted cholesterol therapies are presented as major drivers reducing heart attack incidence.
Youtube — David Sinclair19 Sept 2026
This Supplement Is Older Than Life - And May Help You Live Longer | Lifespan - S2, Ep. 9 (Youtube — David Sinclair)

This Supplement Is Older Than Life - And May Help You Live Longer | Lifespan - S2, Ep. 9

A podcast episode examines glycine, its biological roles, and evidence linking supplementation to tissue repair, cognition, cardiovascular outcomes, and longevity in models.

Key takeaways
  • Glycine supplementation supports collagen synthesis and may improve skin and tissue repair.
  • Animal studies show glycine supplementation extends lifespan and reverses several aging hallmarks.
  • Human evidence links glycine to improved memory, better stroke recovery, and reduced heart attack risk.
Peter Attia Blog19 Sept 2026
Can semaglutide slow aging? (Peter Attia Blog)

Can semaglutide slow aging?

This piece previews a science-focused article examining whether a late-life diabetes drug could influence aging in mice, inviting curiosity about study design and implications.

Key takeaways
  • Female mice started on clinically scaled semaglutide late in life showed a median lifespan of 834 days versus 742 days for controls.
  • Semaglutide-treated mice ate about 24% less, lost primarily fat mass, and had proportionally larger gastrocnemius muscle.
  • Control cohort lifespan was shorter than many historical reports, so findings require replication in independent cohorts and sexes.
MoL Event Pick
International Longevity Summit Madrid 2026 (Madrid, Spain)

International Longevity Summit Madrid 2026

28. SEPT 2026 - 1. OCT 2026 - Madrid, SpainSummit

Madrid summit convening global longevity thinkers, clinicians and innovators across four days of science, networking and public-facing programming.